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Paul G Thomas Selected Research

N- (3- chloro- 7- indolyl)- 1,4- benzenedisulphonamide (E7070)

3/2024RBM39 degrader invigorates natural killer cells to eradicate neuroblastoma despite cancer cell plasticity.
11/2021Targeting the spliceosome through RBM39 degradation results in exceptional responses in high-risk neuroblastoma models.

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Paul G Thomas Research Topics

Disease

78Infections
04/2024 - 04/2005
48Human Influenza (Influenza)
11/2023 - 01/2006
27Neoplasms (Cancer)
03/2024 - 12/2010
18COVID-19
11/2023 - 05/2020
13Inflammation (Inflammations)
01/2023 - 07/2013
11Virus Diseases (Viral Diseases)
07/2023 - 05/2013
7Pneumonia (Pneumonitis)
04/2024 - 09/2014
6Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
12/2022 - 01/2019
4Cytokine Release Syndrome
07/2023 - 01/2017
3Neuroblastoma
03/2024 - 11/2021
3Coinfection
01/2023 - 03/2014
3Autoimmune Diseases (Autoimmune Disease)
01/2022 - 01/2017
2Glioma (Gliomas)
12/2023 - 06/2023
2Hematologic Neoplasms (Hematological Malignancy)
01/2023 - 12/2022
2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
12/2022 - 01/2019
2Breakthrough Infections
01/2022 - 01/2022
2Melanoma (Melanoma, Malignant)
01/2022 - 10/2016
2Residual Neoplasm
01/2021 - 01/2019
2Leukemia
01/2020 - 01/2015
2Persistent Infection
12/2018 - 06/2017
2Communicable Diseases (Infectious Diseases)
12/2018 - 01/2016
2Lung Injury
01/2018 - 01/2016
2Respiratory Syncytial Virus Infections
12/2011 - 02/2011
1Obesity
04/2024
1Herpes Zoster
04/2024
1Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
03/2024
1Viremia
03/2024
1Carcinoma (Carcinomatosis)
03/2024
1Brain Neoplasms (Brain Tumor)
12/2023
1Encephalitis (Encephalitis, Rasmussen)
11/2023
1Post-Acute COVID-19 Syndrome
07/2023
1COVID-19 related pediatric multisystem inflammatory disease
07/2023
1Multiple Organ Failure (MODS)
01/2023
1Chronic Disease (Chronic Diseases)
01/2023

Drug/Important Bio-Agent (IBA)

22EpitopesIBA
04/2024 - 03/2007
22CytokinesIBA
10/2023 - 03/2007
21AntigensIBA
03/2024 - 02/2009
20VaccinesIBA
11/2023 - 04/2005
14Proteins (Proteins, Gene)FDA Link
04/2024 - 01/2006
13Antiviral Agents (Antivirals)IBA
04/2024 - 01/2013
11AntibodiesIBA
11/2023 - 01/2014
8Immunoglobulin G (IgG)IBA
11/2023 - 01/2021
8T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2022 - 02/2011
7Biomarkers (Surrogate Marker)IBA
04/2024 - 07/2013
7EnzymesIBA
11/2023 - 01/2014
7RNA (Ribonucleic Acid)IBA
01/2023 - 01/2014
7Peptides (Polypeptides)IBA
11/2021 - 01/2006
6ImmunosorbentsIBA
11/2023 - 01/2014
6InterferonsIBA
01/2023 - 04/2006
6ChemokinesIBA
01/2022 - 03/2009
5Immunoglobulin A (IgA)IBA
10/2023 - 01/2014
5Messenger RNA (mRNA)IBA
01/2023 - 09/2021
5deoxythymidine 3',5'-bis-(p-nitrophenyl phosphate)IBA
10/2015 - 03/2007
4Influenza Vaccines (Influenza Vaccine)FDA Link
04/2024 - 12/2010
4Immune Checkpoint InhibitorsIBA
12/2023 - 12/2016
4Chimeric Antigen ReceptorsIBA
12/2023 - 11/2022
4Interleukin-6 (Interleukin 6)IBA
12/2020 - 01/2016
3COVID-19 VaccinesIBA
11/2023 - 01/2022
3Neutralizing AntibodiesIBA
11/2023 - 01/2016
3HLA Antigens (Human Leukocyte Antigens)IBA
11/2021 - 12/2020
3Amino AcidsFDA Link
11/2021 - 01/2013
3Oseltamivir (Tamiflu)FDA Link
12/2019 - 01/2015
3Histones (Histone)IBA
12/2019 - 11/2014
2Glycoproteins (Glycoprotein)IBA
04/2024 - 01/2018
2Protein Kinases (Protein Kinase)IBA
04/2024 - 05/2013
2Adrenergic Agents (Adrenergic Drugs)IBA
03/2024 - 03/2024
2N- (3- chloro- 7- indolyl)- 1,4- benzenedisulphonamide (E7070)IBA
03/2024 - 11/2021
2HLA-A Antigens (HLA-A)IBA
11/2023 - 01/2018
2Interleukin-8 (Interleukin 8)IBA
10/2023 - 01/2017
2Interleukin-10 (Interleukin 10)IBA
10/2023 - 01/2017
2Interleukin-18 (Interleukin 18)IBA
10/2023 - 01/2023
2Indicators and Reagents (Reagents)IBA
12/2022 - 07/2008
2Neoplasm Antigens (Tumor Antigens)IBA
10/2022 - 01/2022
2DNA (Deoxyribonucleic Acid)IBA
01/2022 - 01/2020
2mRNA VaccinesIBA
01/2022 - 01/2022
2Monoclonal AntibodiesIBA
09/2021 - 07/2008
2Viral AntigensIBA
01/2021 - 11/2014
2Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
12/2020 - 05/2020
2Peptide Hydrolases (Proteases)FDA Link
11/2020 - 02/2014
2Histocompatibility Antigens Class IIBA
10/2020 - 12/2010
2Interferon-gamma (Interferon, gamma)IBA
05/2020 - 12/2014
2NucleoproteinsIBA
01/2019 - 01/2013
2AcidsIBA
01/2019 - 01/2013
2Phospholipase DIBA
05/2017 - 09/2014
2LipidsIBA
05/2017 - 07/2013
21-dodecylpyridoxal (PLD)IBA
12/2014 - 09/2014
2Phosphotransferases (Kinase)IBA
12/2013 - 05/2013
1LeptinIBA
04/2024
1AdiponectinIBA
04/2024
1Histone DemethylasesIBA
03/2024
1Protein Kinase C-deltaIBA
12/2023
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
12/2023
1Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA
01/2023
1Anti-Bacterial Agents (Antibiotics)IBA
01/2023
1S100A12 ProteinIBA
01/2023

Therapy/Procedure

18Therapeutics
04/2024 - 03/2014
13Immunotherapy
03/2024 - 01/2016
4Drug Therapy (Chemotherapy)
03/2024 - 10/2016
3Cell- and Tissue-Based Therapy (Cell Therapy)
03/2024 - 12/2022
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
03/2024